Effects of the mTOR inhibitor Rapamycin on Monocyte-Secreted Chemokines

BACKGROUND: Mammalian target of rapamycin (mTOR) inhibitors, such as sirolimus and its derivative, everolimus, are potent immunosuppressive and antiproliferative drugs. Inflammatory diseases are characterized by immunological dysfunction, and monocyte recruitment underlies the mechanism of cell dama...

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Bibliografiske detaljer
Main Authors: Lin, Hugo You-Hsien, Chang, Kai-Ting, Hung, Chi-Chih, Kuo, Chang-Hung, Hwang, Shang-Jyh, Chen, Hung-Chun, Hung, Chih-Hsing, Lin, Sheng-Fung
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2014
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4189728/
https://ncbi.nlm.nih.gov/pubmed/25257976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12865-014-0037-0
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