Effects of the mTOR inhibitor Rapamycin on Monocyte-Secreted Chemokines

BACKGROUND: Mammalian target of rapamycin (mTOR) inhibitors, such as sirolimus and its derivative, everolimus, are potent immunosuppressive and antiproliferative drugs. Inflammatory diseases are characterized by immunological dysfunction, and monocyte recruitment underlies the mechanism of cell dama...

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Main Authors: Lin, Hugo You-Hsien, Chang, Kai-Ting, Hung, Chi-Chih, Kuo, Chang-Hung, Hwang, Shang-Jyh, Chen, Hung-Chun, Hung, Chih-Hsing, Lin, Sheng-Fung
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2014
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4189728/
https://ncbi.nlm.nih.gov/pubmed/25257976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12865-014-0037-0
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