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IFITM Proteins Inhibit Entry Driven by the MERS-Coronavirus Spike Protein: Evidence for Cholesterol-Independent Mechanisms

The interferon-inducible transmembrane (IFITM) proteins 1, 2 and 3 inhibit the host cell entry of several enveloped viruses, potentially by promoting the accumulation of cholesterol in endosomal compartments. IFITM3 is essential for control of influenza virus infection in mice and humans. In contras...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Wrensch, Florian, Winkler, Michael, Pöhlmann, Stefan
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: MDPI 2014
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4189045/
https://ncbi.nlm.nih.gov/pubmed/25256397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v6093683
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