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Functional analysis of potential cleavage sites in the MERS-coronavirus spike protein

The Middle East respiratory syndrome-related coronavirus (MERS-CoV) can cause severe disease and has pandemic potential. Therefore, development of antiviral strategies is an important task. The activation of the viral spike protein (S) by host cell proteases is essential for viral infectivity and th...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Kleine-Weber, Hannah, Elzayat, Mahmoud Tarek, Hoffmann, Markus, Pöhlmann, Stefan
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6226446/
https://ncbi.nlm.nih.gov/pubmed/30413791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-34859-w
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