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Functional analysis of potential cleavage sites in the MERS-coronavirus spike protein

The Middle East respiratory syndrome-related coronavirus (MERS-CoV) can cause severe disease and has pandemic potential. Therefore, development of antiviral strategies is an important task. The activation of the viral spike protein (S) by host cell proteases is essential for viral infectivity and th...

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書目詳細資料
發表在:Sci Rep
Main Authors: Kleine-Weber, Hannah, Elzayat, Mahmoud Tarek, Hoffmann, Markus, Pöhlmann, Stefan
格式: Artigo
語言:Inglês
出版: Nature Publishing Group UK 2018
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6226446/
https://ncbi.nlm.nih.gov/pubmed/30413791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-34859-w
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