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Functional analysis of potential cleavage sites in the MERS-coronavirus spike protein

The Middle East respiratory syndrome-related coronavirus (MERS-CoV) can cause severe disease and has pandemic potential. Therefore, development of antiviral strategies is an important task. The activation of the viral spike protein (S) by host cell proteases is essential for viral infectivity and th...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Kleine-Weber, Hannah, Elzayat, Mahmoud Tarek, Hoffmann, Markus, Pöhlmann, Stefan
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6226446/
https://ncbi.nlm.nih.gov/pubmed/30413791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-34859-w
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