Virion Background and Efficiency of Virion Incorporation Determine Susceptibility of Simian Immunodeficiency Virus Env-Driven Viral Entry to Inhibition by IFITM Proteins

Interferon-induced transmembrane proteins (IFITMs) can inhibit the cellular entry of several enveloped viruses, including simian immunodeficiency virus (SIV). The blockade of SIV by IFITMs is isolate specific, raising the question of which parameters impact sensitivity to IFITM. We show that the vir...

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Bibliographic Details
Published in:J Virol
Main Authors: Wrensch, Florian, Hoffmann, Markus, Gärtner, Sabine, Nehlmeier, Inga, Winkler, Michael, Pöhlmann, Stefan
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2017
Subjects:
Virus-Cell Interactions
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5215347/
https://ncbi.nlm.nih.gov/pubmed/27807233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01488-16
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