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Virion Background and Efficiency of Virion Incorporation Determine Susceptibility of Simian Immunodeficiency Virus Env-Driven Viral Entry to Inhibition by IFITM Proteins

Interferon-induced transmembrane proteins (IFITMs) can inhibit the cellular entry of several enveloped viruses, including simian immunodeficiency virus (SIV). The blockade of SIV by IFITMs is isolate specific, raising the question of which parameters impact sensitivity to IFITM. We show that the vir...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Wrensch, Florian, Hoffmann, Markus, Gärtner, Sabine, Nehlmeier, Inga, Winkler, Michael, Pöhlmann, Stefan
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5215347/
https://ncbi.nlm.nih.gov/pubmed/27807233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01488-16
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