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Quantitative sequencing of 5-formylcytosine in DNA at single-base resolution

The cytosine modifications 5-hydroxymethylcytosine (5hmC) and 5-formylcytosine (5fC) were recently found to exist in the genomic DNA of a wide range of mammalian cell types. It is important to now understand their role in normal biological function and disease. Here we introduce reduced bisulfite se...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Booth, Michael J., Marsico, Giovanni, Bachman, Martin, Beraldi, Dario, Balasubramanian, Shankar
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4188980/
https://ncbi.nlm.nih.gov/pubmed/24755596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchem.1893
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