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Intracellular reduction/activation of a disulfide switch in thiosemicarbazone iron chelators
Iron scavengers (chelators) offer therapeutic opportunities in anticancer drug design by targeting the increased demand for iron in cancer cells as compared to normal cells. Prochelation approaches are expected to avoid systemic iron depletion as chelators are liberated under specific intracellular...
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| Hoofdauteurs: | , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2014
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4188698/ https://ncbi.nlm.nih.gov/pubmed/25100578 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c4mt00153b |
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