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Intracellular Iron Chelation Modulates the Macrophage Iron Phenotype with Consequences on Tumor Progression
A growing body of evidence suggests that macrophage polarization dictates the expression of iron-regulated genes. Polarization towards iron sequestration depletes the microenvironment, whereby extracellular pathogen growth is limited and inflammation is fostered. In contrast, iron release contribute...
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| Pubblicato in: | PLoS One |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Public Library of Science
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5091876/ https://ncbi.nlm.nih.gov/pubmed/27806101 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0166164 |
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