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Human tRNA Synthetase Catalytic Nulls with Diverse Functions

Genetic efficiency in higher organisms depends on mechanisms to create multiple functions from single genes. To investigate this question for an enzyme family, we chose aminoacyl tRNA synthetases (AARSs). They are exceptional in their progressive and accretive proliferation of noncatalytic domains a...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Lo, Wing-Sze, Gardiner, Elisabeth, Xu, Zhiwen, Lau, Ching-Fun, Wang, Feng, Zhou, Jie, Mendlein, John D., Nangle, Leslie A., Chiang, Kyle P., Yang, Xiang-Lei, Au, Kin-Fai, Wong, Wing Hung, Guo, Min, Zhang, Mingjie, Schimmel, Paul
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2014
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4188629/
https://ncbi.nlm.nih.gov/pubmed/25035493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1252943
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