Internally deleted human tRNA synthetase suggests evolutionary pressure for repurposing

Aminoacyl-tRNA synthetases (AARSs) catalyze aminoacylation of tRNAs in the cytoplasm. Surprisingly, AARSs also have critical extracellular and nuclear functions. Evolutionary pressure for new functions might be manifested by splice variants that skip only an internal catalytic domain (CD) and link n...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Xu, Zhiwen, Wei, Zhiyi, Zhou, Jie J., Ye, Fei, Lo, Wing-Sze, Wang, Feng, Lau, Ching-Fun, Wu, Jingjing, Nangle, Leslie A., Chiang, Kyle P., Yang, Xiang-Lei, Zhang, Mingjie, Schimmel, Paul
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3485694/
https://ncbi.nlm.nih.gov/pubmed/22958643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2012.08.001
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados