Human tRNA Synthetase Catalytic Nulls with Diverse Functions

Genetic efficiency in higher organisms depends on mechanisms to create multiple functions from single genes. To investigate this question for an enzyme family, we chose aminoacyl tRNA synthetases (AARSs). They are exceptional in their progressive and accretive proliferation of noncatalytic domains a...

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Detaylı Bibliyografya
Asıl Yazarlar: Lo, Wing-Sze, Gardiner, Elisabeth, Xu, Zhiwen, Lau, Ching-Fun, Wang, Feng, Zhou, Jie, Mendlein, John D., Nangle, Leslie A., Chiang, Kyle P., Yang, Xiang-Lei, Au, Kin-Fai, Wong, Wing Hung, Guo, Min, Zhang, Mingjie, Schimmel, Paul
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2014
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Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4188629/
https://ncbi.nlm.nih.gov/pubmed/25035493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1252943
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