Alternative splicing creates two new architectures for human tyrosyl-tRNA synthetase

Many human tRNA synthetases evolved alternative functions outside of protein synthesis. These functions are associated with over 200 splice variants (SVs), most of which are catalytic nulls that engender new biology. While known to regulate non-translational activities, little is known about structu...

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Bibliographic Details
Published in:	Nucleic Acids Res
Main Authors:	Wei, Zhiyi, Xu, Zhiwen, Liu, Xiaotian, Lo, Wing-Sze, Ye, Fei, Lau, Ching-Fun, Wang, Feng, Zhou, Jie J., Nangle, Leslie A., Yang, Xiang-Lei, Zhang, Mingjie, Schimmel, Paul
Format:	Artigo
Language:	Inglês
Published:	Oxford University Press 2016
Subjects:	Molecular Biology
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC4756856/ https://ncbi.nlm.nih.gov/pubmed/26773056 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw002
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Alternative splicing creates two new architectures for human tyrosyl-tRNA synthetase

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