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Crystallization and preliminary X-ray diffraction analysis of the BRPF1 bromodomain in complex with its H2AK5ac and H4K12ac histone-peptide ligands

The bromodomain-PHD finger protein 1 (BRPF1) is an essential subunit of the monocytic leukemia zinc (MOZ) histone acetyltransferase (HAT) complex and is required for complex formation and enzymatic activation. BRPF1 contains a structurally conserved bromodomain, which recognizes specific acetyllysin...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Lubula, Mulu Y., Poplawaski, Amanda, Glass, Karen C.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: International Union of Crystallography 2014
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4188086/
https://ncbi.nlm.nih.gov/pubmed/25286946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2053230X14018433
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