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Purification, crystallization and preliminary X-ray diffraction of the C-terminal bromodomain from human BRD2

BRD2 is a bromodomain-containing BET-family protein that associates with acetylated histones throughout the cell cycle. Although the tertiary structures of the bromodomains involved in histone acetyl transfer are already known, the structures of the BET-type bromodomains, which are required for tigh...

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Bibliografiske detaljer
Main Authors: Umehara, Takashi, Wakamori, Masatoshi, Tanaka, Akiko, Padmanabhan, Balasundaram, Yokoyama, Shigeyuki
Format: Artigo
Sprog:Inglês
Udgivet: International Union of Crystallography 2007
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2335128/
https://ncbi.nlm.nih.gov/pubmed/17620725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309107028473
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