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Purification, crystallization and preliminary X-ray crystallographic analysis of human IL-18 and its extracellular complexes
Interleukin-18 (IL-18), a pro-inflammatory cytokine belonging to the interleukin-1 (IL-1) family, is involved in the pathogenesis of autoimmune/autoinflammatory and allergic diseases such as juvenile idiopathic arthritis and bronchial asthma. IL-18 forms a signalling complex with the IL-18 receptor...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
International Union of Crystallography
2014
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4188078/ https://ncbi.nlm.nih.gov/pubmed/25286938 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2053230X14016926 |
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