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Structural basis for the multiple interactions of the MyD88 TIR domain in TLR4 signaling
Myeloid differentiating factor 88 (MyD88) and MyD88 adaptor-like (Mal) are adaptor molecules critically involved in the Toll-like receptor (TLR) 4 signaling pathway. While Mal has been proposed to serve as a membrane-sorting adaptor, MyD88 mediates signal transduction from activated TLR4 to downstre...
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| Main Authors: | , , , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
National Academy of Sciences
2009
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2693180/ https://ncbi.nlm.nih.gov/pubmed/19506249 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0812956106 |
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