Structural basis for the multiple interactions of the MyD88 TIR domain in TLR4 signaling

Myeloid differentiating factor 88 (MyD88) and MyD88 adaptor-like (Mal) are adaptor molecules critically involved in the Toll-like receptor (TLR) 4 signaling pathway. While Mal has been proposed to serve as a membrane-sorting adaptor, MyD88 mediates signal transduction from activated TLR4 to downstre...

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Detalhes bibliográficos
Main Authors: Ohnishi, Hidenori, Tochio, Hidehito, Kato, Zenichiro, Orii, Kenji E., Li, Ailian, Kimura, Takeshi, Hiroaki, Hidekazu, Kondo, Naomi, Shirakawa, Masahiro
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2693180/
https://ncbi.nlm.nih.gov/pubmed/19506249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0812956106
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