The structural basis for receptor recognition of human interleukin-18

Interleukin (IL)-18 is a proinflammatory cytokine that belongs to the IL-1 family and plays an important role in inflammation. The uncontrolled release of this cytokine is associated with severe chronic inflammatory disease. IL-18 forms a signalling complex with the IL-18 receptor α (Rα) and β (Rβ)...

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Bibliografiska uppgifter
I publikationen:Nat Commun
Huvudupphovsmän: Tsutsumi, Naotaka, Kimura, Takeshi, Arita, Kyohei, Ariyoshi, Mariko, Ohnishi, Hidenori, Yamamoto, Takahiro, Zuo, Xiaobing, Maenaka, Katsumi, Park, Enoch Y., Kondo, Naomi, Shirakawa, Masahiro, Tochio, Hidehito, Kato, Zenichiro
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Pub. Group 2014
Ämnen:
Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4275594/
https://ncbi.nlm.nih.gov/pubmed/25500532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms6340
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