Reduced In Vitro Doxycycline Susceptibility in Plasmodium falciparum Field Isolates from Kenya Is Associated with PfTetQ KYNNNN Sequence Polymorphism

Doxycycline is widely used for malaria prophylaxis by international travelers. However, there is limited information on doxycycline efficacy in Kenya, and genetic polymorphisms associated with reduced efficacy are not well defined. In vitro doxycycline susceptibility profiles for 96 Plasmodium falci...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Achieng, Angela O., Ingasia, Luiser A., Juma, Dennis W., Cheruiyot, Agnes C., Okudo, Charles A., Yeda, Redemptah A., Cheruiyot, Jelagat, Akala, Hoseah M., Johnson, Jacob, Andangalu, Ben, Eyase, Fredrick, Jura, Walter G. Z. O., Kamau, Edwin
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology 2014
Pynciau:
Mechanisms of Resistance
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4187988/
https://ncbi.nlm.nih.gov/pubmed/25070109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02788-13
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