Reduced In Vitro Doxycycline Susceptibility in Plasmodium falciparum Field Isolates from Kenya Is Associated with PfTetQ KYNNNN Sequence Polymorphism

Doxycycline is widely used for malaria prophylaxis by international travelers. However, there is limited information on doxycycline efficacy in Kenya, and genetic polymorphisms associated with reduced efficacy are not well defined. In vitro doxycycline susceptibility profiles for 96 Plasmodium falci...

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Autores principales: Achieng, Angela O., Ingasia, Luiser A., Juma, Dennis W., Cheruiyot, Agnes C., Okudo, Charles A., Yeda, Redemptah A., Cheruiyot, Jelagat, Akala, Hoseah M., Johnson, Jacob, Andangalu, Ben, Eyase, Fredrick, Jura, Walter G. Z. O., Kamau, Edwin
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2014
Materias:
Mechanisms of Resistance
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4187988/
https://ncbi.nlm.nih.gov/pubmed/25070109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02788-13
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