Characterization of a Melamino Nitroheterocycle as a Potential Lead for the Treatment of Human African Trypanosomiasis

This paper reports an evaluation of a melamino nitroheterocycle, a potential lead for further development as an agent against human African trypanosomiasis (HAT). Studies on its efficacy, physicochemical and biopharmaceutical properties, and potential for toxicity are described. The compound previou...

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Autors principals: Giordani, Federica, Buschini, Annamaria, Baliani, Alessandro, Kaiser, Marcel, Brun, Reto, Barrett, Michael P., Pellacani, Claudia, Poli, Paola, Gilbert, Ian H.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2014
Matèries:
Experimental Therapeutics
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4187918/
https://ncbi.nlm.nih.gov/pubmed/25022590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01449-13
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