Novel S-Adenosylmethionine Decarboxylase Inhibitors for the Treatment of Human African Trypanosomiasis

Trypanosomiasis remains a significant disease across the sub-Saharan African continent, with 50,000 to 70,000 individuals infected. The utility of current therapies is limited by issues of toxicity and the need to administer compounds intravenously. We have begun a program to pursue lead optimizatio...

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Bibliografiset tiedot
Päätekijät: Barker, Robert H., Liu, Hanlan, Hirth, Bradford, Celatka, Cassandra A., Fitzpatrick, Richard, Xiang, Yibin, Willert, Erin K., Phillips, Margaret A., Kaiser, Marcel, Bacchi, Cyrus J., Rodriguez, Aixa, Yarlett, Nigel, Klinger, Jeffrey D., Sybertz, Edmund
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology (ASM) 2009
Aiheet:
Experimental Therapeutics
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2681509/
https://ncbi.nlm.nih.gov/pubmed/19289530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01674-08
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