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Identification and Characterization of FTY720 for the Treatment of Human African Trypanosomiasis
The screening of a focused library identified FTY720 (Fingolimod; Gilenya) as a potent selective antitrypanosomal compound active against Trypanosoma brucei gambiense and T. brucei rhodesiense, the causative agents of human African trypanosomiasis (HAT). This is the first report of trypanocidal acti...
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| Publicado no: | Antimicrob Agents Chemother |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4775930/ https://ncbi.nlm.nih.gov/pubmed/26666915 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02116-15 |
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