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Identification and Characterization of FTY720 for the Treatment of Human African Trypanosomiasis
The screening of a focused library identified FTY720 (Fingolimod; Gilenya) as a potent selective antitrypanosomal compound active against Trypanosoma brucei gambiense and T. brucei rhodesiense, the causative agents of human African trypanosomiasis (HAT). This is the first report of trypanocidal acti...
Uloženo v:
| Vydáno v: | Antimicrob Agents Chemother |
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| Hlavní autoři: | , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Society for Microbiology
2016
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4775930/ https://ncbi.nlm.nih.gov/pubmed/26666915 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02116-15 |
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