LcrV Delivered via Type III Secretion System of Live Attenuated Yersinia pseudotuberculosis Enhances Immunogenicity against Pneumonic Plague

Here, we constructed a Yersinia pseudotuberculosis mutant strain with arabinose-dependent regulated and delayed shutoff of crp expression (araC P(BAD) crp) and replacement of the msbB gene with the Escherichia coli msbB gene to attenuate it. Then, we inserted the asd mutation into this construction...

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Hlavní autoři: Sun, Wei, Sanapala, Shilpa, Henderson, Jeremy C., Sam, Shandiin, Olinzock, Joseph, Trent, M. Stephen, Curtiss, Roy
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2014
Témata:
Microbial Immunity and Vaccines
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4187879/
https://ncbi.nlm.nih.gov/pubmed/25114109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.02173-14
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