LcrV Delivered via Type III Secretion System of Live Attenuated Yersinia pseudotuberculosis Enhances Immunogenicity against Pneumonic Plague

Here, we constructed a Yersinia pseudotuberculosis mutant strain with arabinose-dependent regulated and delayed shutoff of crp expression (araC P(BAD) crp) and replacement of the msbB gene with the Escherichia coli msbB gene to attenuate it. Then, we inserted the asd mutation into this construction...

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Detalhes bibliográficos
Main Authors: Sun, Wei, Sanapala, Shilpa, Henderson, Jeremy C., Sam, Shandiin, Olinzock, Joseph, Trent, M. Stephen, Curtiss, Roy
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Microbial Immunity and Vaccines
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4187879/
https://ncbi.nlm.nih.gov/pubmed/25114109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.02173-14
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