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Polymorphisms in the lcrV Gene of Yersinia enterocolitica and Their Effect on Plague Protective Immunity

Current efforts to develop plague vaccines focus on LcrV, a polypeptide that resides at the tip of type III secretion needles. LcrV-specific antibodies block Yersinia pestis type III injection of Yop effectors into host immune cells, thereby enabling phagocytes to kill the invading pathogen. Earlier...

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Autori principali: Miller, Nathan C., Quenee, Lauriane E., Elli, Derek, Ciletti, Nancy A., Schneewind, Olaf
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3318405/
https://ncbi.nlm.nih.gov/pubmed/22252870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.05637-11
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