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Gcn5 and PCAF Regulate PPARγ and Prdm16 Expression To Facilitate Brown Adipogenesis

The acetyltransferase Gcn5 is critical for embryogenesis and shows partial functional redundancy with its homolog PCAF. However, the tissue- and cell lineage-specific functions of Gcn5 and PCAF are still not well defined. Here we probe the functions of Gcn5 and PCAF in adipogenesis. We found that th...

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Bibliographische Detailangaben
Hauptverfasser: Jin, Qihuang, Wang, Chaochen, Kuang, Xianghong, Feng, Xuesong, Sartorelli, Vittorio, Ying, Hao, Ge, Kai, Dent, Sharon Y. R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4187735/
https://ncbi.nlm.nih.gov/pubmed/25071153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00622-14
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