Gcn5 and PCAF Regulate PPARγ and Prdm16 Expression To Facilitate Brown Adipogenesis

The acetyltransferase Gcn5 is critical for embryogenesis and shows partial functional redundancy with its homolog PCAF. However, the tissue- and cell lineage-specific functions of Gcn5 and PCAF are still not well defined. Here we probe the functions of Gcn5 and PCAF in adipogenesis. We found that th...

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Autores principales: Jin, Qihuang, Wang, Chaochen, Kuang, Xianghong, Feng, Xuesong, Sartorelli, Vittorio, Ying, Hao, Ge, Kai, Dent, Sharon Y. R.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2014
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Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4187735/
https://ncbi.nlm.nih.gov/pubmed/25071153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00622-14
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