Gcn5 and PCAF Regulate PPARγ and Prdm16 Expression To Facilitate Brown Adipogenesis

The acetyltransferase Gcn5 is critical for embryogenesis and shows partial functional redundancy with its homolog PCAF. However, the tissue- and cell lineage-specific functions of Gcn5 and PCAF are still not well defined. Here we probe the functions of Gcn5 and PCAF in adipogenesis. We found that th...

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Main Authors: Jin, Qihuang, Wang, Chaochen, Kuang, Xianghong, Feng, Xuesong, Sartorelli, Vittorio, Ying, Hao, Ge, Kai, Dent, Sharon Y. R.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2014
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Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4187735/
https://ncbi.nlm.nih.gov/pubmed/25071153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00622-14
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