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PERK-Dependent Activation of JAK1 and STAT3 Contributes to Endoplasmic Reticulum Stress-Induced Inflammation

Neuroinflammation and endoplasmic reticulum (ER) stress are associated with many neurological diseases. Here, we have examined the interaction between ER stress and JAK/STAT-dependent inflammation in glial cells. We show that ER stress is present in the central nervous system (CNS) concomitant with...

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Autori principali: Meares, Gordon P., Liu, Yudong, Rajbhandari, Rajani, Qin, Hongwei, Nozell, Susan E., Mobley, James A., Corbett, John A., Benveniste, Etty N.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4187715/
https://ncbi.nlm.nih.gov/pubmed/25113558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00980-14
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