Attenuation of PKR-like ER Kinase (PERK) Signaling Selectively Controls Endoplasmic Reticulum Stress-induced Inflammation Without Compromising Immunological Responses

Inflammation and endoplasmic reticulum (ER) stress are associated with many neurological diseases. ER stress is brought on by the accumulation of misfolded proteins in the ER, which leads to activation of the unfolded protein response (UPR), a conserved pathway that transmits signals to restore home...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:J Biol Chem
Hauptverfasser: Guthrie, Lauren N., Abiraman, Kavitha, Plyler, Emily S., Sprenkle, Neil T., Gibson, Sara A., McFarland, Braden C., Rajbhandari, Rajani, Rowse, Amber L., Benveniste, Etty N., Meares, Gordon P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2016
Schlagworte:
Immunology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4957064/
https://ncbi.nlm.nih.gov/pubmed/27226638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.738021
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge