The RimL Transacetylase Provides Resistance to Translation Inhibitor Microcin C

Peptide-nucleotide antibiotic microcin C (McC) is produced by some Escherichia coli strains. Inside a sensitive cell, McC is processed, releasing a nonhydrolyzable analog of aspartyl-adenylate, which inhibits aspartyl-tRNA synthetase. The product of mccE, a gene from the plasmid-borne McC biosynthet...

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Detalhes bibliográficos
Main Authors: Kazakov, Teymur, Kuznedelov, Konstantin, Semenova, Ekaterina, Mukhamedyarov, Damir, Datsenko, Kirill A., Metlitskaya, Anastasija, Vondenhoff, Gaston H., Tikhonov, Anton, Agarwal, Vinayak, Nair, Satish, Van Aerschot, Arthur, Severinov, Konstantin
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4187662/
https://ncbi.nlm.nih.gov/pubmed/25002546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.01584-14
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