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Escherichia coli Peptidase A, B, or N Can Process Translation Inhibitor Microcin C

The heptapeptide-nucleotide microcin C (McC) targets aspartyl-tRNA synthetase. Upon its entry into a susceptible cell, McC is processed to release a nonhydrolyzable aspartyl-adenylate that inhibits aspartyl-tRNA synthetase, leading to the cessation of translation and cell growth. Here, we surveyed E...

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Detalhes bibliográficos
Main Authors: Kazakov, Teymur, Vondenhoff, Gaston H., Datsenko, Kirill A., Novikova, Maria, Metlitskaya, Anastasia, Wanner, Barry L., Severinov, Konstantin
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2293190/
https://ncbi.nlm.nih.gov/pubmed/18223070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.01956-07
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