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MccE Provides Resistance to Protein Synthesis Inhibitor Microcin C by Acetylating the Processed Form of the Antibiotic

The heptapeptide-nucleotide microcin C (McC) is a potent inhibitor of enteric bacteria growth. McC is excreted from producing cells by the MccC transporter. The residual McC that remains in the producing cell can be processed by cellular aminopeptidases with the release of a non-hydrolyzable asparty...

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Detalhes bibliográficos
Main Authors: Novikova, Maria, Kazakov, Teymur, Vondenhoff, Gaston H., Semenova, Ekaterina, Rozenski, Jef, Metlytskaya, Anastasija, Zukher, Inna, Tikhonov, Anton, Van Aerschot, Arthur, Severinov, Konstantin
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2857085/
https://ncbi.nlm.nih.gov/pubmed/20159968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.080192
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