The rho kinase inhibitor Y-27632 improves motor performance in male SOD1(G93A) mice

Disease progression in amyotrophic lateral sclerosis (ALS) is characterized by degeneration of motoneurons and their axons which results in a progressive muscle weakness and ultimately death from respiratory failure. The only approved drug, riluzole, lacks clinical efficacy so that more potent treat...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Günther, René, Saal, Kim-Ann, Suhr, Martin, Scheer, David, Koch, Jan Christoph, Bähr, Mathias, Lingor, Paul, Tönges, Lars
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2014
Fag:
Pharmacology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4187656/
https://ncbi.nlm.nih.gov/pubmed/25339858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2014.00304
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker