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The rho kinase inhibitor Y-27632 improves motor performance in male SOD1(G93A) mice
Disease progression in amyotrophic lateral sclerosis (ALS) is characterized by degeneration of motoneurons and their axons which results in a progressive muscle weakness and ultimately death from respiratory failure. The only approved drug, riluzole, lacks clinical efficacy so that more potent treat...
Tallennettuna:
| Päätekijät: | , , , , , , , |
|---|---|
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
Frontiers Media S.A.
2014
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4187656/ https://ncbi.nlm.nih.gov/pubmed/25339858 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2014.00304 |
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