Aminoglycoside-mediated relaxation of the ductus arteriosus in sepsis-associated PDA

Sepsis is strongly associated with patency of the ductus arteriosus (PDA) in critically ill newborns. Inflammation and the aminoglycoside antibiotics used to treat neonatal sepsis cause smooth muscle relaxation, but their contribution to PDA is unknown. We examined whether: 1) lipopolysaccharide (LP...

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Hlavní autoři: Vucovich, Megan M., Cotton, Robert B., Shelton, Elaine L., Goettel, Jeremy A., Ehinger, Noah J., Poole, Stanley D., Brown, Naoko, Wynn, James L., Paria, Bibhash C., Slaughter, James C., Clark, Reese H., Rojas, Mario A., Reese, Jeff
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2014
Témata:
Integrative Cardiovascular Physiology and Pathophysiology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4187398/
https://ncbi.nlm.nih.gov/pubmed/24993047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00838.2013
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