Aminoglycoside-mediated relaxation of the ductus arteriosus in sepsis-associated PDA

Sepsis is strongly associated with patency of the ductus arteriosus (PDA) in critically ill newborns. Inflammation and the aminoglycoside antibiotics used to treat neonatal sepsis cause smooth muscle relaxation, but their contribution to PDA is unknown. We examined whether: 1) lipopolysaccharide (LP...

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Detalhes bibliográficos
Main Authors: Vucovich, Megan M., Cotton, Robert B., Shelton, Elaine L., Goettel, Jeremy A., Ehinger, Noah J., Poole, Stanley D., Brown, Naoko, Wynn, James L., Paria, Bibhash C., Slaughter, James C., Clark, Reese H., Rojas, Mario A., Reese, Jeff
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2014
Assuntos:
Integrative Cardiovascular Physiology and Pathophysiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4187398/
https://ncbi.nlm.nih.gov/pubmed/24993047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00838.2013
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