Isoprostanes as physiological mediators of transition to newborn life: novel mechanisms regulating patency of the term and preterm ductus arteriosus

BACKGROUND: Increased oxygen tension at birth regulates physiologic events that are essential to postnatal survival, but the accompanying oxidative stress may also generate isoprostanes. We hypothesized that isoprostanes regulate ductus arteriosus (DA) function during postnatal vascular transition....

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Detalhes bibliográficos
Main Authors: Chen, Jian-Xiong, O’Mara, Patrick W., Poole, Stanley D., Brown, Naoko, Ehinger, Noah J., Slaughter, James C., Paria, Bibhash C., Aschner, Judy L., Reese, Jeff
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3586272/
https://ncbi.nlm.nih.gov/pubmed/22565502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/pr.2012.58
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