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Functional chromatography reveals three natural products that target the same protein with distinct mechanisms of action
Access to lead compounds with defined molecular targets continues to be a barrier to the translation of natural product resources. As a solution, we have developed a system that uses discreet, recombinant proteins as the vehicles for natural product isolation. Here, we describe the use of this funct...
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| Główni autorzy: | , , , , , , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
2014
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4187115/ https://ncbi.nlm.nih.gov/pubmed/25125376 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.201402258 |
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