Functional chromatography reveals three natural products that target the same protein with distinct mechanisms of action

Access to lead compounds with defined molecular targets continues to be a barrier to the translation of natural product resources. As a solution, we have developed a system that uses discreet, recombinant proteins as the vehicles for natural product isolation. Here, we describe the use of this funct...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Kang, MinJin, Wu, Tongde, Wijeratne, E. M. Kithsiri, Lau, Eric C., Mason, Damian J., Mesa, Celestina, Tillotson, Joseph, Zhang, Donna D., Gunatilaka, A. A. Leslie, La Clair, James J., Chapman, Eli
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2014
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4187115/
https://ncbi.nlm.nih.gov/pubmed/25125376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.201402258
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg