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Reversibly locked thionucleobase pairs in DNA to study base flipping enzymes

Covalently interstrand cross-linked DNA is an interesting tool to study DNA binding proteins that locally open up the DNA duplex by flipping single bases out of the DNA helix or melting whole stretches of base pairs to perform their function. The ideal DNA cross-link to study protein–DNA interaction...

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書目詳細資料
Main Authors: Beuck, Christine, Weinhold, Elmar
格式: Artigo
語言:Inglês
出版: Beilstein-Institut 2014
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4187101/
https://ncbi.nlm.nih.gov/pubmed/25298797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.10.239
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