Central base pair flipping and discrimination by PspGI

PspGI is a representative of a group of restriction endonucleases that recognize a pentameric sequence related to CCNGG. Unlike the previously investigated Ecl18kI, which does not have any specificity for the central base pair, PspGI prefers A/T over G/C in its target site. Here, we present a struct...

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Bibliographic Details
Main Authors: Szczepanowski, Roman H., Carpenter, Michael A., Czapinska, Honorata, Zaremba, Mindaugas, Tamulaitis, Gintautas, Siksnys, Virginijus, Bhagwat, Ashok S., Bochtler, Matthias
Format: Artigo
Language:Inglês
Published: Oxford University Press 2008
Subjects:
Structural Biology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2577326/
https://ncbi.nlm.nih.gov/pubmed/18829716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkn622
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