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Sequence-dependent enhancement of hydrolytic deamination of cytosines in DNA by the restriction enzyme PspGI

Hydrolytic deamination of cytosines in DNA creates uracil and, if unrepaired, these lesions result in C to T mutations. We have suggested previously that a possible way in which cells may prevent or reduce this chemical reaction is through the binding of proteins to DNA. We use a genetic reversion a...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Carpenter, Michael, Divvela, Pradeep, Pingoud, Vera, Bujnicki, Janusz, Bhagwat, Ashok S.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Oxford University Press 2006
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC1557792/
https://ncbi.nlm.nih.gov/pubmed/16893959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkl545
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