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Reversibly locked thionucleobase pairs in DNA to study base flipping enzymes

Covalently interstrand cross-linked DNA is an interesting tool to study DNA binding proteins that locally open up the DNA duplex by flipping single bases out of the DNA helix or melting whole stretches of base pairs to perform their function. The ideal DNA cross-link to study protein–DNA interaction...

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Detalhes bibliográficos
Main Authors: Beuck, Christine, Weinhold, Elmar
Formato: Artigo
Idioma:Inglês
Publicado em: Beilstein-Institut 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4187101/
https://ncbi.nlm.nih.gov/pubmed/25298797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.10.239
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