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Critical role of DNA intercalation in enzyme-catalyzed nucleotide flipping

Nucleotide flipping is a common feature of DNA-modifying enzymes that allows access to target sites within duplex DNA. Structural studies have identified many intercalating amino acid side chains in a wide variety of enzymes, but the functional contribution of these intercalating residues is poorly...

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Bibliografiske detaljer
Udgivet i:Nucleic Acids Res
Main Authors: Hendershot, Jenna M., O'Brien, Patrick J.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4227769/
https://ncbi.nlm.nih.gov/pubmed/25324304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku919
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