Cardiac-specific suppression of NF-κB signaling prevents diabetic cardiomyopathy via inhibition of the renin-angiotensin system

Activation of NF-κB signaling in the heart may be protective or deleterious depending on the pathological context. In diabetes, the role of NF-κB in cardiac dysfunction has been investigated using pharmacological approaches that have a limitation of being nonspecific. Furthermore, the specific cellu...

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Hlavní autoři: Thomas, Candice M., Yong, Qian Chen, Rosa, Rodolfo M., Seqqat, Rachid, Gopal, Shanthi, Casarini, Dulce E., Jones, W. Keith, Gupta, Sudhiranjan, Baker, Kenneth M., Kumar, Rajesh
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2014
Témata:
Integrative Cardiovascular Physiology and Pathophysiology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4187070/
https://ncbi.nlm.nih.gov/pubmed/25085967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00340.2014
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