Angiotensin type 1a receptor-deficient mice develop diabetes-induced cardiac dysfunction, which is prevented by renin-angiotensin system inhibitors

BACKGROUND: Diabetes-induced organ damage is significantly associated with the activation of the renin-angiotensin system (RAS). Recently, several studies have demonstrated a change in the RAS from an extracellular to an intracellular system, in several cell types, in response to high ambient glucos...

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Autores principales: Yong, Qian Chen, Thomas, Candice M, Seqqat, Rachid, Chandel, Niketa, Baker, Kenneth M, Kumar, Rajesh
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2013
Materias:
Original Investigation
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3830441/
https://ncbi.nlm.nih.gov/pubmed/24215514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2840-12-169
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