Enalapril inhibits tubulointerstitial inflammation and NLRP3 inflammasome expression in BSA-overload nephropathy of rats

AIM: Proteinuria is not only a common marker of renal disease, but also involved in renal tubulointerstitial inflammation and fibrosis. The aim of this study was to investigate the mechanisms underlying the protective effects of enalapril, an ACEI, against nephropathy in rats. METHODS: Wistar rats u...

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Autors principals: Ding, Li-hong, Liu, Dan, Xu, Min, Liu, Hong, Wu, Min, Tang, Ri-ning, Lv, Lin-li, Ma, Kun-ling, Liu, Bi-cheng
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2014
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4186985/
https://ncbi.nlm.nih.gov/pubmed/25152022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2014.66
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