Chargement en cours...
Megalin/Cubulin-Lysosome-mediated Albumin Reabsorption Is Involved in the Tubular Cell Activation of NLRP3 Inflammasome and Tubulointerstitial Inflammation
Albuminuria contributes to the development and progression of chronic kidney disease by inducing tubulointerstitial inflammation (TI) and fibrosis. However, the exact mechanisms of TI in response to albuminuria are unresolved. We previously demonstrated that NLRP3 and inflammasomes mediate albumin-i...
Enregistré dans:
| Publié dans: | J Biol Chem |
|---|---|
| Auteurs principaux: | , , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society for Biochemistry and Molecular Biology
2015
|
| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4505048/ https://ncbi.nlm.nih.gov/pubmed/26025362 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.662064 |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|