FTY720 inhibits tubulointerstitial inflammation in albumin overload-induced nephropathy of rats via the Sphk1 pathway

AIM: FTY720, a new immunomodulatory drug with low cytotoxicity, is currently used to treat multiple sclerosis. In this study, we investigated the effects of FTY720 on inflammatory cell infiltration in albumin overload-induced nephropathy of rats. METHODS: Male Wistar rats were subjected to right-sid...

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Detalhes bibliográficos
Publicado no:Acta Pharmacol Sin
Main Authors: Xu, Min, Liu, Dan, Ding, Li-hong, Ma, Kun-ling, Wu, Min, Lv, Lin-li, Wen, Yi, Liu, Hong, Tang, Ri-ning, Liu, Bi-cheng
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4261119/
https://ncbi.nlm.nih.gov/pubmed/25399649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2014.100
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